Levels of ANX A1 mRNA and protein in PMVECs induced by CBDL-Rat serum at each time point. (A.B) Exposure to CBDL-Rat serum significantly decreased expression of the ANX A1 gene, including the transcript and protein levels in PMVECs (p < 0.05). (C) The mRNA and protein density of the ANX A1 gene for each group is displayed. Each data point represents the mean ± S.E.M. of four independent experiments. * p < 0.05 vs. T1 or T2; # p < 0.05 vs. Group N. Group N: normal rat serum; Group C: CBDL-Rat serum.