Vaccine doses | 1.0Â mg (n=3) | 3.0Â mg (n=3) | Total patients (n=6) | |||
---|---|---|---|---|---|---|
 | Grade | Grade | (%) | |||
 | 1-2 | 3(4) | 1-2 | 3(4) |  |  |
Blood/bone marrow | Â | Â | Â | Â | Â | Â |
   Anemia | 2 | 0 | 2 | 0 | 4 | (67) |
   Thrombocytopenia | 0 | 0 | 1 | 0 | 1 | (17) |
Hepatic | Â | Â | Â | Â | Â | Â |
   Elevated AST | 0 | 0 | 0 | (1) | 1 | (17) |
   Elevated ALT | 0 | 0 | 0 | (1) | 1 | (17) |
Constitutional symptoms | Â | Â | Â | Â | Â | Â |
   Fatigue | 0 | 0 | 3 | 0 | 3 | (50) |
   Fever | 1 | 0 | 1 | 0 | 2 | (33) |
Gastrointestinal | Â | Â | Â | Â | Â | Â |
   Nausea/vomiting | 0 | 0 | 2 | 0 | 2 | (33) |
   Anorexia | 0 | 0 | 2 | 0 | 2 | (33) |
   Constipation | 1 | 0 | 0 | 0 | 1 | (17) |
Dermatology/skin | Â | Â | Â | Â | Â | Â |
   Rash | 3 | 0 | 3 | 0 | 6 | (100) |
   Pruritus | 3 | 0 | 2 | 0 | 5 | (83) |
   Reaction at the injection site | 3 | 0 | 3 | 0 | 6 | (100) |