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Table 1 Data elements

From: Daily cytokine fluctuations, driven by leptin, are associated with fatigue severity in chronic fatigue syndrome: evidence of inflammatory pathology

Participant Age (years) Race/ Ethnicity Income range Employment/Disability status BMI Mode of onset Duration of illness (years) Fatigue severity (0=none, 100=severe) Muscle pain severity (0=none, 100=severe) Joint pain severity (0=none, 100=severe) Sleep quality (0=poor, 100=good) Multi-dimensional fatigue inventory MFI-20§ Fatigue severity scale§ HADS: Depression Sub-score Meets FM criteria Co-morbid conditions Medications
1 54 Caucasian $10,000-19,999 Not reported 18 Acute 35 61 50 46 39 88 6.67 6 Yes Osteoarthritis Aspirin, Levothyroxine
2 53 Caucasian $20,000-29,999 Retired/Disablility 31.6 Acute 15 73 71 70 52 96 6.78 13 Yes Hypothyroid, High Blood Pressure Alprazolam, Amlodipine, Levothyroxine, Valganciclovir, Naproxen, Melatonin, Aspirin, Estradiol
3 53 Caucasian Not reported Retired 25.2 Gradual 30 80 60 41 65 76 6.56 6 Yes Degenerate Arthritis, Spinal Stenosis, Sleep Apnea Estradiol, Valganciclovir, Lidocaine
4 47 Caucasian less than $10,000 Unemployed 25.9 Acute 9 31 6 50 41 81 6.67 3 Yes High Cycling EBV and HHV-6, Chronic Sinus Infections, Chlamidophila Pneumonia Loratadine, Cetirizine, Hydroxyzine, Diphenhydram, Gabapentin, 5- Hydroxytryptophan, St. John's Wort
5 61 Caucasian $10,000-19,999 Unemployed/Disability 35.7 Gradual 7 50 33 32 37 94 7.00 10 No Graves Disease/Hypothyroid, Obesity Bupropion, Estradiol, Fenofibrate, Levothyroxine, Valganciclovir†, Fluoxetine, Acetaminophen
6 60 Caucasian $80,000 or more Employed 20.6 Gradual 5 64 49 42 39 90 5.89 11 Yes None None
7 51 Caucasian $10,000-19,999 Disability 23.3 Gradual 5 81 25 0 71 89 5.89 3 Yes None Acyclovir††
8 29 Caucasian $40,000-49,999 Employed 27.5 Gradual 15 62 63 67 55 NA NA 0 Yes None Topiramate
9 55 Caucasian $60,000-69,999 Retired/Disablility 20.4 Acute 10 74 70 48 55 NA NA 14 Yes None Bupropion, Controlled-Release Morphine, Progesterone, Loratadine, Diazepam, Alprazolam, Estradiol, Sertraline, Zolpidem, Rizatriptan, Ibuprofen, Ketorolac
10 62 Caucasian $30,000-39,99 Not reported 42 Gradual 20 36 25 8 44 84 6.56 3 No Hypothyroid, Obesity, High Blood Pressure, ADHD Olmesartan, Bupropion, Thyroid, Estradiol, Dextroamphetamine and Amphetamine
11 57 Caucasian $20,000-29,999 Employed 33.1 NA NA 0 0 0 71 42 2.22 0 No High Blood Pressure Amlodipine, Asprin
12 48 Caucasian less than $10,000 Unemployed 23 NA NA 18 23 4 70 NA NA 1 No None None
13 51 Caucasian less than $10,000 Employed 21.3 NA NA 30 7 19 54 NA NA 2 No None Prozac
14 58 Caucasian less than $10,000 Employed 25.1 NA NA 0 0 0 67 NA NA 3 No None None
15 52 Asian Not reported Employed 19.7 NA NA 6 1 0 64 48 1.88 0 No None Proton Pump Inhibitor
16 50 Caucasian $50,000-59,999 Employed 20.5 NA NA 0 0 0 96 20 1.22 0 No None None
17 44 Caucasian $30,000-39,999 Employed 25.5 NA NA 5 12 0 77 25 1.77 1 No None None
18 47 African American $80,000 or more Employed 31.6 NA NA 19 9 1 80 28 1.66 2 No Borderline High Blood Pressure, High Cholesterol Zyrtec
19 61 Caucasian $40,000-49,999 Retired 24 NA NA 15 0 0 79 26 1.77 1 No Plantar Fasciitis Loratadine
20 62 Latina $10,000-19,999 Employed 24.5 NA NA 6 5 0 79 22 1.33 1 No None None
  1. Data elements for each of the 20 participants (CFS: #1 – 10, Controls: #11 – 20). Participants self-reported race/ethnicity, income, employment/disability status, height, weight, mode of CFS onset, duration of CFS, co-morbid conditions, and medications. Fatigue, muscle pain, joint pain, and sleep quality were determined by taking the mean from the two-week baseline period of symptom severity assessments. The HADS [14] and Fibromyalgia Assessment Form [15] were administered during the screening visit. §Scores are from an existing database maintained by Stanford’s CFS Research Team. Valganciclovir was prescribed as an experimental treatment for CFS, ††Acyclovir was prescribed for HSV-1 and HSV-2. NA = Not Available.