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Table 3 Morphometrical characteristics of fibroblasts from celiacs and healthy controls

From: Extracellular matrix proteins and displacement of cultured fibroblasts from duodenal biopsies in celiac patients and controls

 

Characteristics of fibroblasts

Parameter

Controls (#12)

Celiacs (#12)

P value

Feret Diameter (μm)*

62.90 ± 21.60

89.00 ± 28.00

< 0.05

Perimeter (μm)

188.30 ± 61.90

252.30 ± 99.80

< 0.05

Area (μm2)

744.60 ± 357.60

933.60 ± 649.30

NS

Circularity index°

0.30 ± 0.20

0.20 ± 0.10

NS

Complexity index (1/μm)&

0.30 ± 0.10

0.40 ± 0.20

NS

  1. * Feret diameter: longest axis length.
  2. ° Circularity index: Feret diameter/short axis length.
  3. & Complexity index: perimeter/area (1/μm); NS, Not significant.