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Table 1 Morphometrical characteristics of intracellular fluorescent signal of type I and IV collagen fibroblasts from celiacs and healthy controls

From: Extracellular matrix proteins and displacement of cultured fibroblasts from duodenal biopsies in celiac patients and controls

  Type I collagen Type IV collagen
Parameter Controls (#12) Celiacs (#12) P value Controls (#12) Celiacs (#12) P value
Feret Diameter (μm) * 53.00 ± 11.00 35.20 ± 5.00 < 0.005 62.90 ± 12.05 32.90 ± 4.90 < 0.0001
Perimeter (μm) 121.30 ± 24.00 107.60 ± 16.80 < 0.005 145.90 ± 27.20 99.60 ± 12.06 < 0.001
Area (μm2) 377.20 ± 86.90 563.40 ± 122.80 < 0.05 375.60 ± 118.60 502.70 ± 98.10 < 0.05
Circularity index° 0.30 ± 0.10 0.62 ± 0.11 < 0.005 0.20 ± 0.06 0.60 ± 0.11 < 0.0001
Complexity index (1/μm)& 0.30 ± 0.03 0.19 ± 0.02 < 0.0001 0.40 ± 0.08 0.20 ± 0.03 < 0.0001
  1. * Feret diameter: longest axis length.
  2. ° Circularity index: Feret diameter/short axis length.
  3. & Complexity index: perimeter/area (1/μm).