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Table 1 Morphometrical characteristics of intracellular fluorescent signal of type I and IV collagen fibroblasts from celiacs and healthy controls

From: Extracellular matrix proteins and displacement of cultured fibroblasts from duodenal biopsies in celiac patients and controls

 

Type I collagen

Type IV collagen

Parameter

Controls (#12)

Celiacs (#12)

P value

Controls (#12)

Celiacs (#12)

P value

Feret Diameter (μm) *

53.00 ± 11.00

35.20 ± 5.00

< 0.005

62.90 ± 12.05

32.90 ± 4.90

< 0.0001

Perimeter (μm)

121.30 ± 24.00

107.60 ± 16.80

< 0.005

145.90 ± 27.20

99.60 ± 12.06

< 0.001

Area (μm2)

377.20 ± 86.90

563.40 ± 122.80

< 0.05

375.60 ± 118.60

502.70 ± 98.10

< 0.05

Circularity index°

0.30 ± 0.10

0.62 ± 0.11

< 0.005

0.20 ± 0.06

0.60 ± 0.11

< 0.0001

Complexity index (1/μm)&

0.30 ± 0.03

0.19 ± 0.02

< 0.0001

0.40 ± 0.08

0.20 ± 0.03

< 0.0001

  1. * Feret diameter: longest axis length.
  2. ° Circularity index: Feret diameter/short axis length.
  3. & Complexity index: perimeter/area (1/μm).