Figure 1From: High EGFR copy number predicts benefits from tyrosine kinase inhibitor treatment for non-small cell lung cancer patients with wild-type EGFRFluorescent in situ hybridization for epidermal growth factor receptor (EGFR) (orange signal) and centromere 7 (green signal) showing low (disomy = A; high triomy = B) copy number per cell (EGFR-FISH negative), high (high polysomy = C; gene amplification = D) copy number per cell (EGFR-FISH positive) (A-D, 1,000×).Back to article page