Figure 2From: ARA290, a non-erythropoietic EPO derivative, attenuates renal ischemia/reperfusion injuryEffect of ARA290 on acute inflammation. Warm ischemia doubled mRNA expression of IL-6 and MCP-1 at 2 minutes prior to reperfusion. ARA290 tends to reduce mRNA expression of IL-6 and MCP-1 relative to baseline only 15 minutes after the first administration of ARA290, indicative of its direct anti-inflammatory effect (p=0.06).Back to article page