Figure 1

Effect of lixisenatide on infarct size and cardiac function in isolated rat hearts subjected to ischemia (45 min) and reperfusion (120 min). (A) infarct to risk area ratio, (B) risk area, and (C, D) selected coronary flow and rate pressure product immediately after onset of reperfusion (5 min) and at the end of reperfusion (120 min). ^*) denotes p < 0.05 versus placebo.