Cardioprotective effect of ritonavir, an antiviral drug, in isoproterenol induced myocardial necrosis: a new therapeutic implication

Table 3 Myocardial TBARS, Nitric oxide, GSH, Catalase and SOD in different experimental groups

Groups	TBARS (nmoles / gm heart wt.)	Nitric oxide (μmole / mg protein)	GSH (mg / gm heart wt.)	Catalase (units / mg protein)	SOD (units / mg protein)
Control	27.99 ± 4.25	0.018 ± 0.001	4.22 ± 0.45	7.82 ± 0.15	313.89 ± 13.69
ISO	47.81 ± 5.70**	0.023 ± 0.001**	3.05 ± 0.09*	5.60 ± 0.14***	245.33 ± 7.45**
ISO + Phz	36.40 ± 6.58	0.019 ± 0.001^†	3.37 ± 0.59	7.98 ± 0.52^††	320.42 ± 12.44^††
ISO + RTV	28.93 ± 4.03^†	0.018 ± 0.001^†	4.75 ± 0.72^†	7.95 ± 0.49^††	372.41 ± 18.80^†††

All the values were expressed Mean ± SEM, (N = 6) * p < 0.05, ** p <0.01, *** p <0.001 vs Control group; ^† p < 0.05, ^{† †} p < 0.01, ^{† † †} p < 0.001 vs ISO group.

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