Skip to main content

Table 1 Basal levels of pS6 in MM tumor and immune cells

From: Development of a robust flow cytometry-based pharmacodynamic assay to detect phospho-protein signals for phosphatidylinositol 3-kinase inhibitors in multiple myeloma

Cell type

CD marker

Location

pS6

PD response

Tumor cells

CD45-; CD38+; CD138+

BMA

+++

Robust

Monocytes

CD45+; CD14+

PB, BMA

+++

Moderate

B cells

CD45+; CD20+

PB, BMA

-

N/A

T cells

CD45+; CD3+

PB, BMA

-

N/A

Back to article page

Journal of Translational Medicine

ISSN: 1479-5876

Contact us