Table 1 Characteristics of the patients according to SLC22A18 promoter methylation and protein expression status
Variables | N = 86 No. (%) | SLC22A18 promoter methylation status, No. (%) | P-value | SLC22A18 protein expression, No. (%) | P-value | ||
|---|---|---|---|---|---|---|---|
Methylated N = 61(71) | Unmethylated N = 25(29) | Positive N = 36(42) | Negative N = 50(58) | ||||
Gender | |||||||
 Male | 46(53) | 36(59) | 10(40) | 0.11 | 21(58) | 25(50) | 0.45 |
 Fmale | 40(47) | 25(41) | 15(60) |  | 15(42) | 25(50) |  |
Age (years) | |||||||
 <45 | 13(15) | 8(13) | 5(20) | 0.42 | 4(11) | 9(18) | 0.38 |
 ≥45 | 73(85) | 53(87) | 20(80) |  | 32(89) | 41(82) |  |
Performance status | |||||||
 <90 | 39(45) | 27(44) | 12(48) | 0.75 | 16(44) | 23(46) | 0.89 |
 ≥90 | 47(55) | 34(56) | 13(52) |  | 20(56) | 27(54) |  |
Extent of surgery | |||||||
 Total | 45(52) | 34(56) | 11(44) | 0.32 | 19(67) | 26(42) | 0.94 |
 Not total | 41(48) | 27(44) | 14(56) |  | 17(33) | 24(58) |  |
MGMT promoter | |||||||
 Unmethylation | 29(34) | 18(30) | 11(44) | 0.20 | 12(33) | 17(34) | 0.95 |
 Methylation | 57(66) | 43(70) | 14(56) |  | 24(67) | 33(66) |  |
TMZ therapy | |||||||
 Yes | 50(58) | 37(61) | 13(52) | 0.46 | 23(64) | 27(54) | 0.36 |
 No | 36(42) | 24(39) | 12(48) |  | 13(36) | 23(46) |  |