Figure 2

Pro-inflammatory cytokines at different stages of tumor progression. Serial serum specimens were collected via submandibular bleeds following urethane doses 5, 8, and 10 and then every four weeks thereafter until study termination. Blood was pooled (n = 6), and the serum was isolated and analyzed for the presence of 20 cytokines. Concentrations represent the mean of pooled samples and bars represent the range. Arrows indicate the points at which L-BLP25 cycles one and two were begun in the L-BLP25 cycle-dependent studies.