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Table 3 Multivariate Cox analyses for DFS and OS of 136 patients with ESCC

From: The expressions of MIF and CXCR4 protein in tumor microenvironment are adverse prognostic factors in patients with esophageal squamous cell carcinoma

Variables DFS (n=136) OS (n=136)
  HR (95% CI) p HR (95% CI) p
MIF in Tumor cells (low/high) 1.689 (1.132-2.521) 0.010* 1.619 (1.084-2.418) 0.018*
CXCR4 in Tumor cells (low/high) 1.708 (1.126-2.591) 0.012* 1.612 (1.072-2.425) 0.022*
MIF in Lymphocytes (low/high) 1.473 (0.999-2.172) 0.050* 1.523 (1.027-2.259) 0.037*
Combination of MIF and CXCR4 in tumor cells (low/mid/high) 1.338 (1.064-1.683) 0.013* 1.263 (1.009-1.583) 0.042*
  1. Note: The Cox proportional hazards regression model contained the significantly different factors in univariate analysis, including gender, WHO grade, T status, N status and TNM stage. HR, hazard ratio; CI, confidence interval; * means P < 0.05.