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Table 2 Univariate analysis of DFS and OS in 136 patients with ESCC

From: The expressions of MIF and CXCR4 protein in tumor microenvironment are adverse prognostic factors in patients with esophageal squamous cell carcinoma

Variables DFS (n=136) OS (n=136)
  HR (95% CI) P HR (95% CI) P
Age, years (62/>62) 0.682 (0.462-1.005) 0.053 0.714 (0.483-1.054) 0.090
Gender (male/female) 0.452 (0.256-0.798) 0.006* 0.417 (0.232-0.747) 0.003*
WHO Grade (1/2/3) 1.362 (1.053-1.763) 0.019* 1.324 (1.023-1.715) 0.033*
Tumor (T) status (1-2/3-4) 1.569 (1.019-2.416) 0.041* 1.508 (0.976-2.332) 0.064
Nodal (N) status (0/1) 2.095 (1.415-3.101) <0.001* 1.998 (1.346-2.965) 0.001*
TNM stage (I-II/III-IV) 1.346 (1.110-1.633) 0.003* 1.318 (1.085-1.601) 0.005*
MIF in tumor cells (low/high) 1.518 (1.028-2.242) 0.036* 1.532 (1.034-2.269) 0.033*
CXCR4 in tumor cells (low/high) 1.537 (1.035-2.283) 0.033* 1.550 (1.041-2.307) 0.031*
MIF in lymphocytes (low/high) 1.548 (1.053-2.275) 0.026* 1.481 (1.003-2.185) 0.048*
CXCR4 in lymphocytes (low/high) 0.738 (0.501-1.085) 0.122 0.715 (0.485-1.055) 0.091
  1. Note: * P < 0.05.