Chemokine CXCL14 is associated with prognosis in patients with colorectal carcinoma after curative resection

Table 4 Univariate and multivariate analyses of stage I/II disease-free survival and stage III/IV overall survival

	Univariate Analysis		Multivariate Analysis		Univariate Analysis		Multivariate Analysis
Clinical Factors	Recurrences/No. of Patients (stage I/II)	Log-Rank P	Risk Ratio (95%CI)	Wald P	Deaths/No. of Patients (stage III/IV)	Log-Rank P	Risk Ratio (95%CI)	Wald P
Sex		0.314	1.0	NS		0.337	1.0	NS
Female	9/37				42/71
Male	9/54				43/64
Age, years		0.999	1.0	NS		<0.001	3.753	<0.001
<70	13/65				58/99		(1.746-8.070)
≥70	5/26				27/36
TNM stage		0.222	1.0	NS		0.084	1.0	NS
p I	0/8
p II	18/83
p III					82/127
p IV					3/8
Tumor invasion		0.408	1.0	NS		0.842	1.0	NS
pT1	0/1
pT2	0/7				3/4
pT3	18/77				79/125
pT4	0/6				3/6
Lymph node NO. /metastasis		0.006	1.0	NS		<.001	4.450	<.001
0-7/pN0	9/25				2/8		(2.675-7.401)
8–12/pN1	4/48				65/105
>12/pN2	5/18				18/22
Grade		0.329	1.0	NS		0.132	1.0	NS
Well	6/28				18/29
Moderate	8/50				55/90
Poor	4/13				12/16
Tumor size, cm		0.049	1.0	0.099		0.249	1.0	NS
<2	2/20				25/37
2-5	12/63				42/72
>5	4/8				18/26
Location	0.164	1.0	NS			0.440	1.0	NS
Colon	11/40				44/75
Rectum	7/51				41/60
CXCL14		0.018	2.92 (1.15-7.40)	0.024		0.003	3.087 (1.866-5.107)	<0.001
Low	10/69				39/68
High	8/22				46/67

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