The level of CXCL14 expression was significantly correlated with TNM stage and histodifferentiation. A, strong immunoreactivity was more likely to present with late-stage CRC compared to early-stage CRC (P < 0.001). Bar, 50 μm. B, poorly differentiated colorectal tumors showed stronger immunoreactivity of CXCL14 than moderately and well differentiated colorectal tumors (P = 0.002). Bar, 25 μm. C and D, comparison of immunohistochemical scores of CXCL14 according to TNM stage (C) and histodifferentiation (D).