Immunoscore | Immunoprofiling | |
---|---|---|
Prognostic/Predictive(?) | Prognostic/Predictive(?) | |
Number of immune markers | 2-4 | 1 – Several |
Immunoscore markers | CD3/CD8 | |
Immunoscore-like markers | CD3/CD8/CD20/FoxP3 | Immune gene signatures |
CD3/CD8/CD45RO | Multiplex assays | |
CD4/CD8/CD68 | CD137, Galectin1, LAG-3, OX40, PD- | |
CD3/CD8/CD20, CD3/GZMB | ||
CD8/FoxP3 | ||
CD8/IL17 | ||
(others) | ||
Possible application | • Staging in colorectal cancer (already tested) | • Prognostic assay |
• Staging in Melanoma, Breast cancer, Ovarian cancer, NSCLC, Prostate cancer, Pancreatic cancer, Head & Neck cancer (to be defined). | • Predictive assay | |
• Personalized immune-treatment |