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Table 2 Predictors of osteopenia/osteoporosis

From: Association between peripheral T-Lymphocyte activation and impaired bone mineral density in HIV-infected patients

  Model 1* Model 2^
  AOR CI 95% p AOR CI 95% p
sex (male) 1.11 0.24-5.17 .9 0.90 0.21-3.82 .9
age (for each additional year) 1.03 0.97-1.10 .3 1.01 0.95-1.07 .7
BMI (for each additional point) 1.00 0.99-1.00 .9 1.00 0.99-1.00 .8
hepatitis co-infection 1.39 0.15-12.7 .8 1.84 0.25-13.4 .5
CD4+ nadir (for 50 cells or more) 1.08 0.88-1.32 .4 1.04 0.87-1.24 .7
time on HAART (for each additional year) 0.92 0.80-1.05 .2 0.93 0.81-1.07 .3
HLA-DR + CD4+ (for each additional %) 1.08 1.01-1.15 .02    
CD28 + CD4+ (for each additional %) 1.06 1.0-1.13 .04    
HLA-DR + CD8+ (for each additional %)     1.06 1.01-1.11 .01
CD127 + CD8+ (for each additional %)     0.94 0.83-1.06 .3
  1. *Model 1: a multivariate logistic regression was performed to explore the association between CD4+ activation and senescence with low BMD, adjusting for demographic and HIV-related parameters. ^Model 2: a multivariate logistic regression was performed to explore the association between activated and central memory CD8+ T cells with low BMD after correction for demographic and HIV-related parameters.