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Table 2 Predictors of osteopenia/osteoporosis

From: Association between peripheral T-Lymphocyte activation and impaired bone mineral density in HIV-infected patients

 

Model 1*

Model 2^

 

AOR

CI 95%

p

AOR

CI 95%

p

sex (male)

1.11

0.24-5.17

.9

0.90

0.21-3.82

.9

age (for each additional year)

1.03

0.97-1.10

.3

1.01

0.95-1.07

.7

BMI (for each additional point)

1.00

0.99-1.00

.9

1.00

0.99-1.00

.8

hepatitis co-infection

1.39

0.15-12.7

.8

1.84

0.25-13.4

.5

CD4+ nadir (for 50 cells or more)

1.08

0.88-1.32

.4

1.04

0.87-1.24

.7

time on HAART (for each additional year)

0.92

0.80-1.05

.2

0.93

0.81-1.07

.3

HLA-DR + CD4+ (for each additional %)

1.08

1.01-1.15

.02

   

CD28 + CD4+ (for each additional %)

1.06

1.0-1.13

.04

   

HLA-DR + CD8+ (for each additional %)

   

1.06

1.01-1.11

.01

CD127 + CD8+ (for each additional %)

   

0.94

0.83-1.06

.3

  1. *Model 1: a multivariate logistic regression was performed to explore the association between CD4+ activation and senescence with low BMD, adjusting for demographic and HIV-related parameters. ^Model 2: a multivariate logistic regression was performed to explore the association between activated and central memory CD8+ T cells with low BMD after correction for demographic and HIV-related parameters.