An immunophenotypic analysis of peripheral blood T-cell activation was performed on sixty-two patients (41 LBMD patients and 21 NBMD patients). Patients with LBMD are shown in the circles, and patients with NBMD are shown in the triangles. The median percentage of HLADR + on CD4+ (A) and CD8+ (B) T-cells. The median percentage of CD38+ on CD4+ (C) and CD8+ (D) T-cells. The median percentage of HLADR + CD38+ on CD4+ (E) and CD8+ (F) T-cells. The bars correspond to the IQR. The expression of CD127 on CD4+ and CD8+ T-cells was evaluated for all seventy-eight patients. The median percentage of CD127 + CD4+ (G) and CD8+ (H) T-cells in PBMCs. The bars correspond to the IQR.