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Figure 1 | Journal of Translational Medicine

Figure 1

From: T-cell activation by treatment of cancer patients with EMD 521873 (Selectikine), an IL-2/anti-DNA fusion protein

Figure 1

Kinetics of subpopulations of leukocytes in patients treated with Selectikine. Absolute counts (109 cells/L) of total leukocytes, lymphocytes, monocytes and neutrophils from patients treated at increasing doses of Selectikine (0.075, 0.15, 0.225, 0.3, 0.45, 0.6 and 0.9 mg/kg). Geometric mean values of absolute counts are shown for each dose-group, until discontinuation. Blood was drawn during each treatment cycle at the following time points: day 1 before start of Selectikine infusion and on day 3 and day 8 after start of Selectikine infusion. Black boxes on the x-axis represent the treatment, i.e. the 1-h iv infusions of Selectikine during three consecutive days per cycle.

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