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Figure 5 | Journal of Translational Medicine

Figure 5

From: Targeting of interleukin-13 receptor α2 for treatment of head and neck squamous cell carcinoma induced by conditional deletion of TGF-β and PTEN signaling

Figure 5

MDSCs were decreased by IL-13-PE treatment in Tgfbr1/Pten 2cKO mice. (A) Representative flow profile showing decreased populations of CD11b+Gr-1+ cells through IL-13-PE treatment. (B) Quantification of flow cytometry results. IL-13-PE treated mice are compared with both the saline injected Tgfbr1/Pten 2cKO tumor-bearing controls and the Tgfbr1f/f/Ptenf/f mice without tumors. MDSCs were significantly reduced with IL-13-PE treatment (P value < 0.005).

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