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Table 1 Patient characteristics and hormonal profiles

From: Comparison of the diagnostic values of circulating steroid hormones, VEGF-A, PIGF, and ADAM12 in women with ectopic pregnancy

  n Age GA E2 P4 E2/P4 T β-hCG
   (years) (days) (pg/mL) (ng/mL)   (ng/mL) (mIU/mL)
Menstrualcycle phase         
 Proliferative 30 25.90 ± 0.50 - 37.99 ± 4.76 0.90 ± 0.12 0.06 ± 0.012 0.21 ± 0.02 -
 Early secretive 13 25.85 ± 0.55 - 16.84 ± 4.52 2.59 ± 0.82 0.01 ± 0.004 0.15 ± 0.02 -
 Mid secretive 20 25.10 ± 0.40 - 14.57 ± 4.15 5.05 ± 1.02 0.02 ± 0.008▲▲ 0.15 ± 0.05 -
 Late secretive 15 25.80 ± 1.09 - 14.83 ± 2.97 3.80 ± 1.15 0.01 ± 0.003▲▲ 0.15 ± 0.04 -
Intrauterine pregnancy         
 Early 14 26.36 ± 1.46 50.57 ± 1.36 176.61 ± 21.87 13.00 ± 1.65 0.02 ± 0.003 0.53 ± 0.05 21320.76 ± 1700.47
 Middle 10 27.33 ± 1.03 115.50 ± 4.06 211.91 ± 42.04 15.81 ± 1.03 0.01 ± 0.003 0.27 ± 0.05 17727.61 ± 2925.63
 Late 13 27.58 ± 1.08 255.11 ± 8.16 499.62 ± 87.98### 89.93 ± 11.99 ### 0.01 ± 0.003 0.70 ± 0.08 12311.79 ± 1644.37##
 Post-term delivery 10 30.70 ± 1.27 - 39.86 ± 5.35 6.62 ± 0.74 0.01 ± 0.001 0.37 ± 0.04 3691.29 ± 816.94 ###
Ectopic pregnancy         
 Before surgery         
β-hCG< 1,000mIU/mL 17 29.06 ± 1.13 48.00 ± 4.31 36.09 ± 5.00 3.65 ± 0.77 0.02 ± 0.003 0.41 ± 0.05 813.45 ± 350.12
β-hCG ≥ 1,000mIU/mL 15 31.93 ± 1.56 47.20 ± 3.87 33.31 ± 6.45 6.97 ± 1.30 0.01 ± 0.008* 0.48 ± 0.04 6505.13 ± 1999.57
Total 32 30.41 ± 0.96 47.61 ± 2.86 34.70 ± 4.01 5.37 ± 0.82 0.02 ± 0.004 0.45 ± 0.03 3573.05 ± 1092.31
 After surgery         
β-hCG< 500mIU/mL 16 29.13 ± 1.28 - 54.53 ± 15.90 2.04 ± 0.38 0.03 ± 0.006* 0.37 ± 0.06 237.15 ± 36.15
β-hCG ≥ 500mIU/mL 6 29.50 ± 1.73 - 26.03 ± 9.77 2.43 ± 0.38 0.01 ± 0.003 * 0.26 ± 0.07 1792.07 ± 353.56
Total 22 29.23 ± 1.02 - 46.75 ± 12.05 2.14 ± 0.29 0.02 ± 0.005 0.34 ± 0.05 703.63 ± 192.92
  1. GA, gestational age. Data are presented as mean ± SEM. Statistical analysis was performed using SPSS version 16.0 for Windows (SPSS Inc., Chicago, IL).
  2. A nonparametric, unpaired test (Kruskal-Wallis test) followed by Dunnett'spost hoc test was used for comparison of continuous variables.
  3. ▲ p<0.05, ▲▲ p<0.01 vs. the proliferative phase of the endometrial cycle; ## p<0.01, ### p<0.001 vs. the early stage of intrauterine pregnancy;
  4. * p<0.05 vs. ectopic pregnancy (before surgery, β-hCG< 1,000mIU/mL).