Table 2 The associaition of MACC1 mRNA expression with the baseline clinical presentation in advanced HCC patients
Variables | All cases (n = 120) | MACC1 mRNA high expression (total cases = 60) [n(%)] | MACC1 mRNA low expression (total cases = 60) [n(%)] | P value |
|---|---|---|---|---|
Gender | ||||
 Male | 106 | 52(87) | 54(90) | 0.7761 |
Age | Â | Â | Â | Â |
 ≥ 48 years | 60 | 25(42) | 38(63) | 0.0283 |
Tumor size | Â | Â | Â | Â |
 ≥ 6 cm | 60 | 37(62) | 18(30) | 0.0010 |
HCC thrombus | Â | Â | Â | Â |
 Portal trunk | 49 | 32(53) | 17(28) | 0.0093 |
HCC number | Â | Â | Â | Â |
 Multinodular | 53 | 32(53) | 21(35) | 0.0432 |
Differentiation | Â | Â | Â | Â |
 Well | 20 | 8(13) | 12(20) | 0.0347 |
 Moderately | 50 | 20(34) | 30(50) |  |
 Poorly | 50 | 32(53) | 18(30) |  |
Serum AFP | Â | Â | Â | Â |
 ≥1368 | 85 | 41(68) | 44(73) | 0.6879 |
HBV DNA | Â | Â | Â | Â |
 Positive | 76 | 36(60) | 40(67) | 0.4486 |
Child-Pugh | Â | Â | Â | Â |
 A | 58 | 31(52) | 27(45) | 0.4650 |
 B | 62 | 29(48) | 33(55) |  |