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Figure 3 | Journal of Translational Medicine

Figure 3

From: High intratumoral metastasis-associated in colon cancer-1 expression predicts poor outcomes of cryoablation therapy for advanced hepatocellular carcinoma

Figure 3

Nuclear expression of MACC1 protein and overall survival after cryoablation therapy. A. The expression of MACC1 protein detected by immunohistochemistry (×400). a. Normal control liver tissue showed a weak MACC1expression in cytoplasm. b. A HCC case showed a mainly cytoplasmic MACC1 expression in tumor tissue (arrowhead). c. Another case with both weak cytoplasmic and sporadic nuclear MACC1 expression(arrowhead). d. The predominant nulear MACC1 expression in the tumorous tissue of a HCC patient (arrowhead). B. Kaplan–Meier estimates of time to progression in patients with nuclear MACC1 expression vs. those with cytoplasmic MACC1 expression (p < 0.001). C: Kaplan–Meier estimates of overall survival time in patients with nuclear MACC1 expression vs. those with cytoplasmic MACC1 expression (p < 0.01).

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