Figure 2

Expression of MACC1 and the outcomes of advanced HCC after receiving cryoablation therapy. A: MACC1 mRNA expression measured by RT-PCR in tumorous tissue from patients with advanced HCC (upper panel, T1-T6) vs. normal liver tissue from controls (upper panel, N1 and N2), and the lower panel was β-actin as internal controls. B: Mean MACC1 mRNA expression in tumorous tissue from patients with advanced HCC (right) vs. that in control (left) by real-time RT-PCR. C: Kaplan–Meier estimates of time to progression in patients with higher MACC1 mRNA expression vs. those with lower MACC1 mRNA expression (p < 0.001). D: Kaplan–Meier estimates of overall survival time in patients with higher MACC1 mRNA expression vs. those with lower MACC1 mRNA expression (p < 0.019).