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Table 1 Demographic and clinical characteristics of HNSCC patients included in the study (n = 70)

From: TIMP3 and CCNA1 hypermethylation in HNSCC is associated with an increased incidence of second primary tumors

Characteristic

 

N

%

 

Median, range

59.2-90

 

Age

> 60 y.o.

38

54.3

 

≤ 60 y.o.

32

45.7

Gender

Male

56

80.0

 

Female

14

20.0

Tobacco

Yes

61

87.1

Consumption

No

9

12.9

Alcohol

Yes

58

82.9

Consumption

No

12

17.1

Tumor

Oral cavity

37

52.9

Site

Larynx

21

30.0

 

Oropharynx

8

11.4

 

Hypopharynx

4

5.7

cT Stage

cT1/cT2

27

38.6

 

cT3/cT4

43

61.4

cN Stage

cN0

29

41.4

 

cN+

41

58.6

First curative

Surgery

13

18.6

treatment

Radiotherapy

3

4.3

 

Surgery + Radio

34

48.6

 

Surgery + Radio + Chemo

9

12.9

 

Radio + Chemo

11

15.7

Second primary

Yes

7

10.0

Tumor

No

63

90.0

Recurrence

Yes

32

45.7

 

No

38

54.3