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Table 1 Demographic and clinical characteristics of HNSCC patients included in the study (n = 70)

From: TIMP3 and CCNA1 hypermethylation in HNSCC is associated with an increased incidence of second primary tumors

Characteristic   N %
  Median, range 59.2-90  
Age > 60 y.o. 38 54.3
  ≤ 60 y.o. 32 45.7
Gender Male 56 80.0
  Female 14 20.0
Tobacco Yes 61 87.1
Consumption No 9 12.9
Alcohol Yes 58 82.9
Consumption No 12 17.1
Tumor Oral cavity 37 52.9
Site Larynx 21 30.0
  Oropharynx 8 11.4
  Hypopharynx 4 5.7
cT Stage cT1/cT2 27 38.6
  cT3/cT4 43 61.4
cN Stage cN0 29 41.4
  cN+ 41 58.6
First curative Surgery 13 18.6
treatment Radiotherapy 3 4.3
  Surgery + Radio 34 48.6
  Surgery + Radio + Chemo 9 12.9
  Radio + Chemo 11 15.7
Second primary Yes 7 10.0
Tumor No 63 90.0
Recurrence Yes 32 45.7
  No 38 54.3