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Table 2 Multivariate analysis of metastasis free survival (MFS) and overall survival (OS) of 203 colon cancer patients

From: TPX2 is a novel prognostic marker for the growth and metastasis of colon cancer

Variable

Multivariate analysis (MFS)

Multivariate analysis (OS)

 

p value

HR

CI (95%)

p value

HR

CI (95%)

AJCC stage (I/II vs. III/IV)

<0.001

3.7

1.8-7.5

<0.001

4.6

2.5-8.4

Histologically poorer grade †

0.256

1.6

0.7-3.7

<0.001

3.0

1.7-5.3

Vessel invasion (no vs. yes)

0.022

2.9

1.1-7.4

0.176

1.5

0.8-3.1

TPX2 (negative vs. positive)

0.001

3.7

1.7-8.1

0.006

2.2

1.2-3.9

  1. N.S., Not significant; HR, Hazard ratio; CI, Confidence interval; “Histologically poorer grade” corresponded to signet ring cell carcinoma, mucinous adenocarcinoma, and poorly differentiated adenocarcinoma.