Table 1 Association of RKIP expression in main tumor with clinicopathological features (n = 114)
Feature | Â | Total N (%) | Frequency N (%) | P-value | |
|---|---|---|---|---|---|
| Â | Â | Â | Low (n = 33; 29.0%) | High (n = 81; 71.1%) | Â |
Sex (n = 113) | Female | 52 (46.0) | 17 (53.1) | 35 (43.2) | 0.4573 |
| Â | Male | 61 (54.0) | 15 (46.9) | 46 (56.8) | Â |
Age at diagnosis (yrs) (n = 112) | Median (min, max) | 65 (35–84) | 65 (42–83) | 65 (35–84) | 0.8265 |
Tumor size (cm) (n = 109) | Median (min, max) | 3.0 (1.2-10) | 3.0 (1.3-6.5) | 3.0 (1.2-10) | 0.5498 |
pT classification (n = 112) | pT1-2 | 10 (8.9) | 0 (0.0) | 10 (12.5) | 0.0599° |
| Â | pT3-4 | 102 (91.1) | 32 (100.0) | 70 (87.5) | Â |
Tumor grade (n = 114) | G1-2 | 16 (14.0) | 2 (6.1) | 14 (17.3) | 0.205 |
| Â | G3 | 98 (86.0) | 31 (93.9) | 67 (82.7) | Â |
pN classification (n = 112) | pN0 | 20 (17.9) | 5 (15.6) | 15 (18.8) | 0.9068 |
| Â | pN1-2 | 92 (82.1) | 27 (84.4) | 65 (81.3) | Â |
pM classification (n = 112) | pM0 | 103 (92.0) | 28 (87.5) | 75 (93.8) | 0.4749 |
| Â | pM1 | 9 (8.0) | 4 (12.5) | 5 (6.3) | Â |
Pn classification (n = 110) | Pn0 | 1 (0.9) | 0 (0.0) | 1 (1.3) | 1.0 |
| Â | Pn1 | 109 (99.1) | 32 (100.0) | 77 (98.7) | Â |
Lymphatic invasion (n = 112) | Negative | 21 (18.8) | 4 (12.5) | 17 (21.3) | 0.4215 |
| Â | Positive | 91 (81.3) | 28 (87.5) | 63 (78.8) | Â |
Venous invasion (n = 112) | Negative | 88 (78.6) | 24 (75.0) | 64 (80.0) | 0.7431 |
| Â | Positive | 24 (21.4) | 8 (25.0) | 16 (20.0) | Â |
R classification (n = 111) | R0 | 78 (70.3) | 21 (65.6) | 57 (72.2) | 0.6511 |
| Â | R1 | 33 (29.7) | 11 (34.4) | 22 (27.9) | Â |
Adjuvant chemo (n = 105) | Untreated | 3 (2.9) | 0 (0.0) | 3 (4.1) | 0.6204 |
| Â | Treated | 102 (97.1) | 31 (100.0) | 71 (96.0) | Â |
Tumor budding 10-in-10 | Low-grade | 33 (30.8) | 3 (10.3) | 30 (38.5) | 0.0048 * |
(n = 107) | High-grade | 77 (69.2) | 26 (89.7) | 48 (61.5) | Â |
Intratumoral budding | Negative/Low | 48 (42.9) | 9 (27.3) | 39 (49.4) | 0.0373 ** |
(n = 112) | Medium/High | 64 (57.1) | 24 (72.7) | 40 (50.6) | Â |