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Figure 4 | Journal of Translational Medicine

Figure 4

From: Loss of Raf-1 kinase inhibitor protein (RKIP) is strongly associated with high-grade tumor budding and correlates with an aggressive phenotype in pancreatic ductal adenocarcinoma (PDAC)

Figure 4

Examples of whole tissue sections of PDAC cases immunostained for RKIP (x200). A: positive immunostaining for RKIP in PDAC. Note the absence of tumor buds. B: Normal pancreatic tissue (upper left) with retained RKIP-positivity. Reduced RKIPexpression in the adjacent PDAC. C: Reduced RKIP-expression in PDAC and absent RKIPexpression in the tumor buds (arrows).

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