Figure 1From: Loss of Raf-1 kinase inhibitor protein (RKIP) is strongly associated with high-grade tumor budding and correlates with an aggressive phenotype in pancreatic ductal adenocarcinoma (PDAC) AE1/AE3 (Pancytokeratin) and H&E staining in PDAC to demonstrate the presence of tumor budding (x200): A (H&E) and B (Pancytokeratin): Low-grade tumor budding; C (H&E) and D (Pancytokeratin): High-grade tumor budding. Back to article page