Figure 6

RSV action on IGF and ERKs signaling pathways during differentiation phases. A) Western Blot analysis shows how RSV treatments cause a tendency to increase levels of Pro-IGF-1 R protein and IGF-1 R protein during differentiation. B) In the last phase of differentiation, RSV promotes AKT activation. C) Furthermore, RSV stimuli enhances ERK pathways in all differentiation phases. D) As shown in the panel, RSV seems to cause a significant improve in AMPK protein content during all phase of differentiation and, in the end of differentiation, RSV also promotes AMPK activation. Significance: * p ≤ 0.05; ** p ≤ 0.01. Representative immunoblots of analyzed proteins are shown.