Figure 6
Expression of PTTG1 abrogates the anti-migratory functions of miR-655. (a) Transfection with pcDNA3.1-PTTG1 and the miR-655 mimics increased PTTG1 expression. (b) Transfection with pcDNA3.1-PTTG1 and the miR-655 mimics increased the average number of migrating cells, abrogating the effects of the miR-655 mimics on decreasing cell numbers. Blank, non-transfected cells; NC, cells transfected with scrambled miR-655 negative control; miR-655, cells transfected with miR-655 mimics. *P < 0.05 compared to control.