Figure 2

Expression levels of PTTG1 in ESCC tissues and adjacent non-tumor tissues. (a) Compared with adjacent non-tumor tissues, PTTG1 expression levels in ESCC tissues were significantly higher (P < 0.05). (b) Among ESCC tissues, expression levels of PTTG1 in cases with lymph nodes positive for metastases were higher than those in cases with lymph nodes negative for metastases (P < 0.05). (c) Kaplan–Meier curves of the clinical outcome for PTTG1. Primary ESCCs with moderate to strong PTTG1 expression (>0.7770) had significantly worse survival than did those with weak PTTG1 expression (<0.7770) (P < 0.05, log-rank test). T: tumor tissue (n = 34); N: adjacent non-tumor tissue (n = 34). ^*P < 0.05 compared to the control group.