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Table 1 Change in expression of BMSC genes during co-culture with leukemia cells

From: Leukemia cells induce changes in human bone marrow stromal cells

Up-regulated genesa

Down-regulated genesa

Gene symbol

Fold change

Genes symbol

Fold change

IL8

19.9

ANGPT2

-3.4

CXCL1

19.7

CSRNP3

-2.8

IL1B

8.8

TMEM26

-2.7

CXCL3

7.6

GPR85

-2.6

CCL2

7.3

F2RL2

-2.6

CXCL2

6.3

FOSB

-2.5

ICAM1

5.2

PROCK3

-2.4

SERPINB2

4.6

AP4E1

-2.4

PTGS2

4.5

EVC

-2.3

  1. aComparison of co-cultured and mono-cultured BMSCs (p-value < 0.05).
  2. The genes with the greatest fold change are shown.