Figure 8

CCL2 and IL-8 levels increase in supernatants from BMSCs co-cultured with leukemia cells: comparison of the effects of BMSCs from 3 different donors. BMSC mono-culture (black bars), TF-1 (1), TF-1a (2) and K562 (3) leukemia cell mono-culture (white bars) and BMSC/leukemia cell transwell co-culture (black and white stripped bars) supernatants were harvested after 48 h. The amount (pg/ml) of CCL2 and IL-8 was measured by an ELISA assay. The sample labeling legend is at the top left. The results of 3 experiments with BMSCs from three healthy donors (BMSC006, BMSC002 and BMSC003) are shown.