Parameters
| |
n
|
INI1
|
P value
|
---|
Neg (%)
|
Low (%)
|
High (%)
|
---|
Age
|
≤60
|
22
|
1 (4.5)
|
12 (54.5)
|
9 (41)
|
0.456
|
|
>60
|
112
|
14 (12.5)
|
63 (56.2)
|
35 (31.3)
| |
Sex
|
F
|
49
|
9 (18.4)
|
21 (42.6)
|
19 (39)
|
0.056
|
|
M
|
85
|
6 (7.1)
|
54 (63.5)
|
25 (29.4)
| |
Location
|
Proximal
|
51
|
5 (9.8)
|
34 (66.6)
|
12 (23.6)
|
0.136
|
|
Distal
|
83
|
10 (12)
|
41 (49.4)
|
32 (38.6)
| |
Histology
|
ADC
|
108
|
10 (9.2)
|
62 (57.4)
|
36 (33.4)
|
0.667
|
|
A-Muc
|
17
|
3 (17.6)
|
9 (52.9)
|
5 (29.5)
| |
|
Other
|
9
|
2 (22.2)
|
4 (44.4)
|
3 (33.3)
| |
Grade
|
Well/mod
|
109
|
7 (6.4)
|
67 (61.5)
|
35 (32.1)
|
0.003*
|
|
Poor
|
25
|
8 (32)
|
8 (32)
|
9 (36)
| |
N stage
|
N0
|
88
|
7 (7.9)
|
51 (62.5)
|
30 (29.6)
|
0.387
|
|
N1
|
24
|
3 (12.5)
|
14 (58.3)
|
7 (29.2)
| |
|
N2
|
22
|
5 (22.7)
|
10 (45.4)
|
7 (31.9)
| |
LiverMet
|
Negative
|
93
|
4 (4.3)
|
58 (62.4)
|
31 (33.3)
|
0.001*
|
|
Positive
|
41
|
11 (26.8)
|
17 (41.4)
|
13 (31.8)
| |
Stage
|
I
|
12
|
0
|
5 (41.6)
|
7 (58.4)
|
0.002*
|
|
II
|
63
|
3 (4.8)
|
42 (66.6)
|
18 (28.6)
| |
|
III
|
20
|
1 (5)
|
12 (60)
|
7 (35)
| |
|
IV
|
39
|
11 (28.2)
|
16 (41)
|
12 (30.8)
| |
Total
| |
134
|
15 (11)
|
75 (56)
|
44 (33)
| |
- Tumor classification was based on the TNM (Tumor-Node-Metastasis) system, according to the criteria of the International Union Against Cancer (UICC).
- Abbreviations: Proximal caecum, ascending and transverse colon, Distal descending and sigmoid colon, rectum, Adc adenocarcinoma, AD-Muc adenocarcinoma with a mucinous component below 50%, Other squamous or rhabdoid, Well/mod well and moderately differentiated, Poor poorly differentiated adenocarcinoma, Liver Met Liver metastasis.*Chi-square statistic significant at the 0.01 level.