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Table 1 Correlation between SMARCB1/INI1 expression pattern and patients’ clinico-pathological parameters

From: The chromatin remodelling component SMARCB1/INI1 influences the metastatic behavior of colorectal cancer through a gene signature mapping to chromosome 22

Parameters

 

n

INI1

P value

Neg (%)

Low (%)

High (%)

Age

≤60

22

1 (4.5)

12 (54.5)

9 (41)

0.456

 

>60

112

14 (12.5)

63 (56.2)

35 (31.3)

 

Sex

F

49

9 (18.4)

21 (42.6)

19 (39)

0.056

 

M

85

6 (7.1)

54 (63.5)

25 (29.4)

 

Location

Proximal

51

5 (9.8)

34 (66.6)

12 (23.6)

0.136

 

Distal

83

10 (12)

41 (49.4)

32 (38.6)

 

Histology

ADC

108

10 (9.2)

62 (57.4)

36 (33.4)

0.667

 

A-Muc

17

3 (17.6)

9 (52.9)

5 (29.5)

 
 

Other

9

2 (22.2)

4 (44.4)

3 (33.3)

 

Grade

Well/mod

109

7 (6.4)

67 (61.5)

35 (32.1)

0.003*

 

Poor

25

8 (32)

8 (32)

9 (36)

 

N stage

N0

88

7 (7.9)

51 (62.5)

30 (29.6)

0.387

 

N1

24

3 (12.5)

14 (58.3)

7 (29.2)

 
 

N2

22

5 (22.7)

10 (45.4)

7 (31.9)

 

LiverMet

Negative

93

4 (4.3)

58 (62.4)

31 (33.3)

0.001*

 

Positive

41

11 (26.8)

17 (41.4)

13 (31.8)

 

Stage

I

12

0

5 (41.6)

7 (58.4)

0.002*

 

II

63

3 (4.8)

42 (66.6)

18 (28.6)

 
 

III

20

1 (5)

12 (60)

7 (35)

 
 

IV

39

11 (28.2)

16 (41)

12 (30.8)

 

Total

 

134

15 (11)

75 (56)

44 (33)

 
  1. Tumor classification was based on the TNM (Tumor-Node-Metastasis) system, according to the criteria of the International Union Against Cancer (UICC).
  2. Abbreviations: Proximal caecum, ascending and transverse colon, Distal descending and sigmoid colon, rectum, Adc adenocarcinoma, AD-Muc adenocarcinoma with a mucinous component below 50%, Other squamous or rhabdoid, Well/mod well and moderately differentiated, Poor poorly differentiated adenocarcinoma, Liver Met Liver metastasis.*Chi-square statistic significant at the 0.01 level.