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Table 1 Correlation between SMARCB1/INI1 expression pattern and patients’ clinico-pathological parameters

From: The chromatin remodelling component SMARCB1/INI1 influences the metastatic behavior of colorectal cancer through a gene signature mapping to chromosome 22

Parameters   n INI1 P value
Neg (%) Low (%) High (%)
Age ≤60 22 1 (4.5) 12 (54.5) 9 (41) 0.456
  >60 112 14 (12.5) 63 (56.2) 35 (31.3)  
Sex F 49 9 (18.4) 21 (42.6) 19 (39) 0.056
  M 85 6 (7.1) 54 (63.5) 25 (29.4)  
Location Proximal 51 5 (9.8) 34 (66.6) 12 (23.6) 0.136
  Distal 83 10 (12) 41 (49.4) 32 (38.6)  
Histology ADC 108 10 (9.2) 62 (57.4) 36 (33.4) 0.667
  A-Muc 17 3 (17.6) 9 (52.9) 5 (29.5)  
  Other 9 2 (22.2) 4 (44.4) 3 (33.3)  
Grade Well/mod 109 7 (6.4) 67 (61.5) 35 (32.1) 0.003*
  Poor 25 8 (32) 8 (32) 9 (36)  
N stage N0 88 7 (7.9) 51 (62.5) 30 (29.6) 0.387
  N1 24 3 (12.5) 14 (58.3) 7 (29.2)  
  N2 22 5 (22.7) 10 (45.4) 7 (31.9)  
LiverMet Negative 93 4 (4.3) 58 (62.4) 31 (33.3) 0.001*
  Positive 41 11 (26.8) 17 (41.4) 13 (31.8)  
Stage I 12 0 5 (41.6) 7 (58.4) 0.002*
  II 63 3 (4.8) 42 (66.6) 18 (28.6)  
  III 20 1 (5) 12 (60) 7 (35)  
  IV 39 11 (28.2) 16 (41) 12 (30.8)  
Total   134 15 (11) 75 (56) 44 (33)  
  1. Tumor classification was based on the TNM (Tumor-Node-Metastasis) system, according to the criteria of the International Union Against Cancer (UICC).
  2. Abbreviations: Proximal caecum, ascending and transverse colon, Distal descending and sigmoid colon, rectum, Adc adenocarcinoma, AD-Muc adenocarcinoma with a mucinous component below 50%, Other squamous or rhabdoid, Well/mod well and moderately differentiated, Poor poorly differentiated adenocarcinoma, Liver Met Liver metastasis.*Chi-square statistic significant at the 0.01 level.