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Figure 6 | Journal of Translational Medicine

Figure 6

From: The chromatin remodelling component SMARCB1/INI1 influences the metastatic behavior of colorectal cancer through a gene signature mapping to chromosome 22

Figure 6

The top ranked genes, identified in Cohort I, map to the long arm of chromosome 22 and are closely linked to SMARCB1/INI1. (A) Top genes and biological functions that varied most in terms of differential expression across tumor samples displaying SMARCB1/INI1 down (Neg) or up-regulation (High). (B) The top deregulated genes (BCR, MIF, COMT and MCM5) with the highest statistically significant p values are located on the long (q) arm of chromosome 22 close to SMARCB1/INI1.

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