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Table 4 Hazard ratios of CRC risk defined by different tumour characteristics in relation to height, weight and hip circumference in men

From: Influence of anthropometric factors on tumour biological characteristics of colorectal cancer in men and women: a cohort study

Tumour characteristics Quartiles Height Weight Hip
Number of cases   Cases RR Cases RR Cases RR
Positive nuclear beta-catenin 1 40 1.00 29 1.00 26 1.00
2 36 0.97(0.61-1.55) 42 1.41(0.86-2.29) 33 1.28(0.76-2.18)
3 33 0.71(0.44-1.14) 35 1.15(0.69-1.93) 45 1.55(0.93-2.57)
4 42 1.15(0.73-1.81) 45 1.53(0.94-2.49) 47 1.39(0.84-2.30)
  p trend   0.877   0.180   0.182
Negative nuclear beta-catenin 1 14 1.00 19 1.00 17 1.00
2 26 2.13(1.09-4.16) 19 1.02(0.53-1.94) 11 0.65(0.30-1.40)
3 32 1.94(1.00-3.75) 26 1.31(0.71-2.43) 33 1.87(1.02-3.42)
4 27 1.90(0.96-3.79) 35 1.70(0.94-3.07) 38 1.46(0.79-2.70)
  p trend   0.122   0.048   0.036
CyclinD1 positive 1 45 1.00 40 1.00 36 1.00
2 46 1.16(0.76-1.77) 49 1.23(0.80-1.89) 32 0.91(0.56-1.48)
3 53 1.02(0.67-1.54) 44 1.08(0.69-1.68) 61 1.57(1.02-2.41)
4 52 1.25(0.82-1.90) 63 1.57(1.04-2.39) 67 1.38(0.90-2.12)
  p trend   0.442   0.058   0.034
CyclinD1 negative 1 10 1.00 8 1.00 7 1.00
2 15 1.48(0.66-3.34) 12 1.39(0.57-3.42) 12 1.65(0.65-4.21)
3 13 1.00(0.43-2.32) 17 1.85(0.79-4.34) 16 2.12(0.87-5.18)
4 17 1.52(0.68-3.43) 18 1.78(0.76-4.22) 20 1.90(0.78-4.62)
  p trend   0.513   0.151   0.159
p53 positive (>50%) 1 22 1.00 20 1.00 15 1.00
2 32 1.64(0.93-2.90) 26 1.27(0.70-2.30) 22 1.48(0.76-2.90)
3 32 1.31(0.74-2.31) 33 1.42(0.79-2.54) 38 2.29(1.23-4.26)
4 33 1.65(0.93-2.92) 40 1.85(1.06-3.23) 44 2.12(1.14-3.92)
  p trend   0.191   0.026   0.009
P53 negative (<50%) 1 32 1.00 27 1.00 27 1.00
2 30 1.02(0.62-1.70) 36 1.33(0.79-2.22) 22 0.82(0.46-1.46)
3 33 0.84(0.51-1.39) 27 1.06(0.61-1.83) 39 1.36(0.82-2.27)
4 36 1.13(0.68-1.87) 41 1.48(0.88-2.48) 43 1.15(0.69-1.91)
  p trend   0.845   0.251   0.288
MSI 1 5 1.00 4 1.00 5 1.00
2 9 2.07(0.69-6.20) 7 1.76(0.51-6.05) 5 0.94(0.27-3.26)
3 5 0.98(0.28-3.42) 7 1.91(0.55-6.60) 6 1.06(0.32-3.51)
4 8 1.79(0.55-5.77) 9 2.36(0.70-7.96) 11 1.45(0.49-4.32)
  p trend   0.630   0.176   0.431
MSS 1 48 1.00 46 1.00 39 1.00
2 51 1.16(0.77-1.74) 51 1.09(0.73-1.65) 39 1.03(0.65-1.61)
3 59 1.02(0.69-1.53) 52 1.07(0.71-1.62) 64 1.54(1.02-2.33)
4 58 1.25(0.83-1.87) 67 1.38(0.93-2.05) 74 1.40(0.93-2.11)
  p trend   0.411   0.126   0.038
  1. Adjusted for age, level of education, smoking habits and alcohol consumption.