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Table 2 Hazard ratios of CRC risk defined by different tumour characteristics in relation to height, weight and hip circumference in women

From: Influence of anthropometric factors on tumour biological characteristics of colorectal cancer in men and women: a cohort study

Tumour characteristics Quartiles Height Weight Hip
Number of cases   Cases RR Cases RR Cases RR
Positive nuclear beta-catenin 1 31 1.00 22 1.00 19 1.00
2 56 1.34(0.86-2.08) 39 1.50(0.89-2.52) 38 1.41(0.81-2.46)
3 39 1.32(0.82-2.13) 46 2.04(1.22-3.41) 37 1.28(0.73-2.26)
4 32 1.17(0.70-1.96) 51 1.87(1.12-3.10) 64 1.93(1.14-3.26)
  p trend   0.593   0.010   0.014
Negative nuclear beta-catenin 1 20 1.00 19 1.00 21 1.00
2 30 1.13(0.64-2.00) 32 1.46(0.82-2.57) 21 0.72(0.39-1.32)
3 26 1.33(0.74-2.40) 22 1.17(0.63-2.17) 30 1.03(0.58-1.81)
4 27 1.56(0.86-2.84) 30 1.31(0.73-2.33) 31 0.88(0.50-1.55)
  p trend   0.113   0.599   0.985
CyclinD1 positive 1 39 1.00 35 1.00 34 1.00
2 70 1.36(0.92-2.02) 54 1.32(0.86-2.02) 45 0.92(0.59-1.44)
3 53 1.47(0.97-2.23) 56 1.57(1.03-2.41) 57 1.11(0.72-1.70)
4 52 1.62(1.05-2.49) 69 1.60(1.06-2.42) 78 1.28(0.85-1.93)
  p trend   0.031   0.019   0.110
CyclinD1 negative 1 12 1.00 6 1.00 6 1.00
2 14 0.80(0.37-1.73) 12 1.70(0.63-4.54) 11 1.42(0.52-3.85)
3 12 0.89(0.39-1.99) 14 2.38(0.91-6.22) 11 1.49(0.55-4.07)
4 8 0.61(0.24-1.53) 14 1.96(0.75-5.12) 18 2.13(0.83-5.48)
  p trend   0.365   0.155   0.103
p53 positive (>50%) 1 30 1.00 25 1.00 19 1.00
2 46 1.16(0.73-1.84) 32 1.07(0.63-1.80) 32 1.19(0.67-2.10)
3 32 1.10(0.67-1.83) 34 1.31(0.77-2.20) 34 1.19(0.67-2.10)
4 21 0.78(0.43-1.39) 38 1.21(0.72-2.00) 44 1.31(0.76-2.28)
  p trend   0.431   0.370   0.364
P53 negative (<50%) 1 25 1.00 16 1.00 21 1.00
2 40 1.39(0.82-2.37) 35 1.92(1.06-3.47) 25 0.85(0.48-1.53)
3 33 1.64(0.94-2.84) 37 2.36(1.31-4.26) 35 1.18(0.68-2.04)
4 39 2.17(1.25-3.76)* 45 2.36(1.33-4.21) 52 1.47(0.87-2.47)
  p trend   0.004   0.004   0.042
MSI 1 11 1.00 8 1.00 9 1.00
2 14 1.01(0.46-2.23) 12 1.35(0.55-3.13) 9 0.68(2.271.71)
3 9 0.96(0.39-2.33) 11 1.49(0.60-3.71) 13 0.9(0.40-2.21)
4 11 1.43(0.61-3.38) 14 1.49(0.62-3.59) 14 0.81(0.34-1.90)
  p trend   0.477   0.387   0.864
MSS 1 41 1.00 30 1.00 27 1.00
2 67 1.20(0.81-1.78) 58 1.64(0.05-2.55) 50 1.33(0.83-2.13)
3 56 1.39(0.92-2.09) 55 1.79(1.14-2.80) 52 1.34(0.84-2.13)
4 48 1.28(0.83-1.97) 69 1.87(1.21-2.88) 83 1.85(1.18-2.88)
  p trend   0.203   0.008   0.005
  1. Adjusted for age, level of education, smoking habits and alcohol consumption.
  2. *Heterogeneity analysis with p < 0.05.