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Table 3 Amino acid concentrations in postoperative serum

From: Tumor-dependent increase of serum amino acid levels in breast cancer patients has diagnostic potential and correlates with molecular tumor subtypes

Amino acid

Serum concentration [μg/mL]

Fold difference

P-value

Trend

  

BrCA [n = 38]

HD [n = 10]

   

Aspartic acid

Asp

22.51 ± 8.4

21.16 ± 7.9

1.06

  

Glutamic acid

Glu

188.19 ± 101.8

96.71 ± 35.6

1.95

0.037

Higher in BrCA

Asparagine

Asn

69.50 ± 25.3

67.43 ± 15.6

1.03

  

Serine

Ser

220.99 ±73.4

225.64 ± 43.7

0.98

  

Glutamine

Gln

632.40 ± 146.7

703.62 ± 126.3

0.90

  

Citrulline

Cit

55.67 ± 19.1

43.22 ± 8.4

1.29

  

Arginine

Arg

210.54 ± 57.8

180.39 ± 38.5

1.17

  

Alanine

Ala

795.24 ± 257.6

648.57 ± 205.4

1.23

  

Tyrosine

Tyr

123.16 ± 44.5

96.26 ± 25.0

1.28

  

Valine

Val

411.64 ± 123.4

320.08 ± 35.8

1.29

0.037

Higher in BrCA

Phenylalanine

Phe

117.79 ± 31.5

106.87 ± 22.4

1.10

  

Isoleucine

Ile

118.02 ± 48.3

85.11 ± 17.5

1.39

  

Leucine

Leu

218.70 ± 81.0

170.95 ± 35.1

1.28

  

Ornithine

Orn

157.55 ± 44.6

160.92 ± 39.8

0.98

  

Lysine

Lys

451.55 ± 146.7

478.04 ± 101.1

0.94

  
  1. Serum concentrations are shown as means and standard deviations. All p-values are adjusted for both age and BMI by linear regression. A P-value <0.05 was considered significant.