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Table 1 Data and immunophenotype of AML FAB-M1 patient BMMCs

From: NK cells from an AML patient have recovered in remission and reached comparable cytolytic activity to that of a healthy monozygotic twin mediated by the single-chain triplebody SPM-2

Gender

Female

Age:

21 years old

Diagnosed with:

AML FAB-M1; AML without maturation according to WHO classification [42]

Blast titer:

89.7% blast in the marrow at diagnosis

Case history

 

One course of induction chemotherapy following HAM protocol high dose cytarabine with mitoxantrone [49]

Current status:

Complete remission acheived by induction chemotherapy (HAM)

Myeloid cells % (in blast gate)

Co-expression (cross-lineage) % (in blast gate)

CD 34

89.6%

CD34/CD56

47.9%

CD 33

<19%

CD34/CD7

12.3%

CD 123

n.d. at diagnosis

CD34/HLA-DR

90.5%

CD 117

< 1%

CD34/CD7

12.3%

CD 38

89.9%

  

cy MPO

41.7

  
  1. n.d. not determined.
  2. Cy MPO cytoplasmic myeloperoxidase; flourescent marker enzyme for the myeloid lineage.