Table 1 pH i and pH e in normal and cancer cells: apoptosis and antiapoptosis
Normal cells | Cancer cells | |
|---|---|---|
( pH i < pH e ) | ( pH i > pH e ) | |
(“proton gradient reversal”) | ||
Intracellular pH (pH i ) | 6.99-7.05 | 7.12-7.7 |
(Pathological antiapoptosis) | ||
Extracellular/ | ||
interstitial pH (pH e ) | 7.35-7.45 | 6.2-6.9 |
pH i <6-6.5 | (Therapeutic apoptosis) |