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Figure 3 | Journal of Translational Medicine

Figure 3

From: Wnt signaling blockage inhibits cell proliferation and migration, and induces apoptosis in triple-negative breast cancer cells

Figure 3

iCRT-3 effectively inhibits cell proliferation in BT-549 cells in a dose- and time-dependent manner. Cells were treated with vehicle (DMSO) or each of five Wnt inhibitors (iCRT-3, iCRT-5, iCRT-14, IWP-4, and XAV-939) at the indicated concentrations. Cell index values were continuously measured for 48 hours at intervals of 15 minutes using an xCELLigence instrument. Data represent mean ± SEM of three independent experiments (**p < 0.01).

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