Table 1 The correlation between miR-138 expression and clinicopathological parameters of colorectal cancer
From: Down-regulation of miR-138 promotes colorectal cancer metastasis via directly targeting TWIST2
miR-138 expression | ||||
|---|---|---|---|---|
Clinipathological parameters | Cases (n = 187) | Low (n = 93) | High (n = 94) | P* |
Age (years) | ||||
≤56 | 93 | 44(47.3%) | 49(52.7%) | 0.510 |
>56 | 94 | 49(52.1%) | 45(47.9%) | |
Sex | ||||
male | 104 | 55(52.9%) | 49(47.1%) | 0.335 |
female | 83 | 38(45.8%) | 45(54.2%) | |
CEA Level | ||||
0 ~ 5 ng/ml | 99 | 40(40.4%) | 59(59.6%) | 0.428 |
>5 ng/ml | 88 | 32(36.4%) | 56(63.6%) | |
CA199 Level | ||||
0 ~ 35 u/ml | 136 | 65(47.8%) | 71(52.2%) | 0.254 |
>35 u/ml | 47 | 27(57.4%) | 20(42.6%) | |
Tumor Site | ||||
Colon | 101 | 47(46.5%) | 54(53.5%) | 0.343 |
Rectum | 86 | 46(53.5%) | 40(46.5%) | |
Tumor Size (cm) | ||||
≤5 | 122 | 60(49.2%) | 62(50.8%) | 0.466 |
>5 | 62 | 29(46.8%) | 33(53.2%) | |
Differentiation | ||||
Well/Moderate | 144 | 61(42.4%) | 83(57.6%) | 0.209 |
Poor | 43 | 27(62.8%) | 16(37.2%) | |
pN | ||||
0 | 109 | 37(33.9%) | 72(66.1%) | 0.000* |
≥1 | 78 | 56(71.8%) | 22(28.2%) | |
pT | ||||
T1 + T2 | 47 | 27(46.9%) | 20(53.1%) | 0.105 |
T3 + T4 | 141 | 79(56.0%) | 62(44.0%) | |
Distant metastasis | ||||
M0 | 161 | 79(49.1%) | 82(50.9%) | 0.002* |
M1 | 26 | 22(84.6%) | 4(15.4%) | |