Table 1 Effect of IGF-I treatment on bone morphometry and serum biochemistry

Femur weight (mg)

33.10 ± 2.45

25.50 ± 2.40*

30.16 ± 2.84

Length (mm)

10.15 ± 0.44

9.25 ± 0.85

9.43 ± 0.63

Transversal diameter (mm)

1.05 ± 0.05

1.00 ± 0.05

1.02 ± 0.03

Surface (mm²)

10.60 ± 0.22

9.65 ± 1.14

9.64 ± 0.57

Alkaline phosphatase (U/dL)

378.14 ± 21.37

321.15 ± 19.92*

349.76 ± 13.07

Osteocalcin (ng/mL)

191.71 ± 5.41

164.81 ± 11.73*

185.14 ± 22.82

Osteoprotegerin (ng/mL)

3.15 ± 0.56

2.32 ± 0.28

3.31 ± 0.77

Leptin (ng/mL)

3.20 ± 0.35

2.61 ± 0.27

3.00 ± 0.45