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Table 4 Overview of selected literature

From: Maintenance of “stem cell” features of cartilage cell sub-populations during in vitro propagation

Ref. no. Cell source Sorting Selective culture Clonality Potency
      Adipogenic Osteogenic Chondrogenic
[2] degenerated IVD endplate no agarose no +/- + +
[3] degenerated AF and NP CD 133 +/- no no +/- +/- +
[6] degenerated NP no no no - + +
[8] articular cartilage no agarose yes (cluster) +/- +/- +/-
  (ACI surgery)       
[26] normal articular cartilage no TGFb1, FGF-2, PDGF-BB yes (n = 20 clones) 20% of clones 25% of clones 60% of clones
     2 A/O/C    
[26] normal articular cartilage no no yes (n = 7 clones) 57% of clones 28% of clones 57% of clones
     1 A/O/C    
[28] articular cartilage (knee surgery) no fibronectin coating, osteogenic differentiation in pellet culture yes +/- + +
[29] OA cartilage CD166 +/- no no +/- + +
[58] articular cartilage no no yes (n = 53) +/- + +
  (ACI surgery)    17 A/O/C    
[59] OA cartilage no no   not done - +
[60] normal, OA cartilage CD 155+/CD166+ no no +/- + +
[61] normal, OA cartilage Hoechst dye 33342 no no tissue immunostaining - +/- +
presented study normal, OA cartilage, IVD W5C5 +/-W8B2 +/- no no +/- +/- +
  1. +/- = differentiation either only by gene expression or only spotty distribution in Oil Red staining or mineral deposition or chondrogenesis.