Table 4 Overview of selected literature
From: Maintenance of “stem cell” features of cartilage cell sub-populations during in vitro propagation
Ref. no. | Cell source | Sorting | Selective culture | Clonality | Potency | ||
|---|---|---|---|---|---|---|---|
Adipogenic | Osteogenic | Chondrogenic | |||||
[2] | degenerated IVD endplate | no | agarose | no | +/- | + | + |
[3] | degenerated AF and NP | CD 133 +/- | no | no | +/- | +/- | + |
[6] | degenerated NP | no | no | no | - | + | + |
[8] | articular cartilage | no | agarose | yes (cluster) | +/- | +/- | +/- |
(ACI surgery) | |||||||
[26] | normal articular cartilage | no | TGFb1, FGF-2, PDGF-BB | yes (n = 20 clones) | 20% of clones | 25% of clones | 60% of clones |
2 A/O/C | |||||||
[26] | normal articular cartilage | no | no | yes (n = 7 clones) | 57% of clones | 28% of clones | 57% of clones |
1 A/O/C | |||||||
[28] | articular cartilage (knee surgery) | no | fibronectin coating, osteogenic differentiation in pellet culture | yes | +/- | + | + |
[29] | OA cartilage | CD166 +/- | no | no | +/- | + | + |
[58] | articular cartilage | no | no | yes (n = 53) | +/- | + | + |
(ACI surgery) | 17 A/O/C | ||||||
[59] | OA cartilage | no | no | not done | - | + | |
[60] | normal, OA cartilage | CD 155+/CD166+ | no | no | +/- | + | + |
[61] | normal, OA cartilage | Hoechst dye 33342 | no | no tissue immunostaining | - | +/- | + |
presented study | normal, OA cartilage, IVD | W5C5 +/-W8B2 +/- | no | no | +/- | +/- | + |