Figure 1

MiR-370 enhanced HHT-induced cell apoptosis in K562 cells. Cells were harvested 72 h after transfection of miR-370 mimics and incubation with 0.015 μM HHT or both. NC represents random oligonucleotides for the negative control of miR-370 mimics. Flow cytometry of K562 cells by double-staining with propidium iodide (PI) and Annexin V. The proportions of apoptotic cells are in the upper right corners of Q2 and Q4 cells. Q2 is late apoptosis and Q4 early apoptosis. Results are from 3 independent experiments.