Table 1 Basal variables of morbid obese subjects
From: Preserved endothelial function in human obesity in the absence of insulin resistance
Characteristic | Non-insulin resistant (N=20) | Insulin resistant (N=32) | P values |
|---|---|---|---|
Clinical | |||
Age (years) | 42.9±2.9 | 42.3±1.7 | 0.837 |
Sex (M/F) | 4/16 | 13/19 | 0.123 |
Body mass index (kg/m2) | 46.2±1.0 | 47.4±1.1 | 0.427 |
Waist circumference (cm) | 117.78±2.7 | 127.87±2.5 | 0 .012 |
MetS (%) | 33.3 | 64.3 | 0 .04 |
Diabetes mellitus type 2 (%) | 0.0 | 37.5 | 0 .002 |
Hypertension (%) | 20.0 | 37.5 | 0.183 |
Dyslipidemia (%) | 25.0 | 21.9 | 0.795 |
Active smokers (%) | 20.0 | 31.3 | 0.374 |
Chemical | |||
Fasting glucose (mg/dl) | 89.6±1.9 | 97.3±3.8 | 0.128 |
HbA1c (%) | 5.5±0.06 | 5.9±0.1 | 0.023 |
Total cholesterol (mg/dl) | 180.5±6.5 | 164.5±7.1 | 0.129 |
HDL cholesterol (mg/dl) | 45.3±2.7 | 37.0±1.8 | 0.009 |
LDL cholesterol (mg/dl) | 107.7±6.8 | 99.9±6.9 | 0.449 |
Ratio (TC/HDL) | 4.13±0.2 | 4.7±0.2 | 0 .169 |
Triglycerides (mg/dl) | 109.0±7.7 | 134.2±9.9 | 0.077 |
Fasting insulin (μU/ml) | 10.1±0.6 | 29.8±3.0 | <0 .001 |
HOMA-IR | 2.3±0.1 | 7.3±0.8 | <0 .001 |
CRP (mg/l) | 5.6±0.9 | 10.9±1.3 | 0. 002 |
Treatment | |||
Hypoglycemic drugs (%) | 11.8 | 35.7 | 0.078 |
Hypotensive drugs (%) | 29.4 | 35.7 | 0.664 |
Lipid-lowering drugs (%) | 0.0 | 6.7 | 0.162 |