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Figure 4 | Journal of Translational Medicine

Figure 4

From: Preserved endothelial function in human obesity in the absence of insulin resistance

Figure 4

Role of inflammation on endothelial dysfunction in morbid obese subjects with insulin resistance (IR-MO). Effects of preincubation with the iNOS inhibitor, 1400W (10 μmol/l) (A), the COX inhibitor, indomethacin (10 μmol/l) (B), and the anti-TNF-α, infliximab (100 μmol/l) (C) on the relaxant response to bradykinin (BK) in isolated mesenteric microvessels from IR-MO. Data are expressed as mean±SEM of the percentage of the contraction elicited by K+. N= the number of subjects/n= the number of vascular segments. *p< 0.05 vs IR-MO subjects by two-factors ANOVA.

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