Colorectal cancer
|
---|
|
NO. of patients
|
NKG2D
|
NKp30
|
NKp46
|
Perforin
|
KIR3DL1
|
---|
| |
%
|
P
|
%
|
P
|
%
|
P
|
%
|
P
|
%
|
P
|
---|
Histological grade
| | | | | | | | | | | |
Well/Moderately
|
20
|
89.0 ± 3.7
|
< 0.01 U
|
39.5 ± 19.3
|
ns T
|
56.0 ± 25.8
|
ns T
|
83.9 ± 11.6
|
< 0.05 U
|
20.1 ± 15.9
|
ns U
|
Poorly
|
12
|
77.9 ± 13.3
| |
47.8 ± 19.2
| |
53.6 ± 21.8
| |
63.5 ± 22.8
| |
18.6 ± 6.6
| |
Depth of invasion
*
| | | | | | | | | | | |
Tis/T1/T2/T3
|
7
|
88.9 ± 4.3
|
ns U
|
57.0 ± 12.4
|
< 0.05 T
|
71.4 ± 19.5
|
< 0.05 T
|
87.7 ± 13.0
|
< 0.05 U
|
20.7 ± 11.1
|
ns U
|
T4
|
25
|
83.7 ± 10.9
| |
38.6 ± 19.2
| |
50.5 ± 23.5
| |
73.1 ± 19.6
| |
19.2 ± 13.8
| |
Lymph node metastasis
| | | | | | | | | | | |
Absent
|
18
|
89.3 ± 4.2
|
< 0.01 U
|
39.3 ± 20.2
|
ns U
|
63.8 ± 24.8
|
< 0.05 U
|
86.2 ± 8.8
|
< 0.01 U
|
21.2 ± 16.8
|
ns U
|
Present
|
14
|
79.1 ± 12.4
| |
46.9 ± 18.1
| |
43.8 ± 18.1
| |
63.5 ± 21.5
| |
17.4 ± 5.5
| |
Blood vessel invasion
| | | | | | | | | | | |
Absent
|
25
|
86.5 ± 7.8
|
ns U
|
42.0 ± 20.1
|
ns U
|
53.9 ± 24.1
|
ns U
|
77.8 ± 18.2
|
ns U
|
19.0 ± 14.5
|
ns U
|
Present
|
7
|
78.9 ± 15.0
| |
44.6 ± 17.9
| |
59.1 ± 25.2
| |
70.7 ± 23.0
| |
21.4 ± 6.3
| |
Nerve invasion
| | | | | | | | | | | |
Absent
|
27
|
84.0 ± 11.7
|
ns U
|
40.9 ± 18.6
|
ns T
|
55.7 ± 23.3
|
ns U
|
75.8 ± 19.7
|
ns U
|
20.8 ± 13.7
|
ns U
|
Present
|
5
|
84.7 ± 3.1
| |
51.8 ± 23.1
| |
51.4 ± 30.4
| |
78.8 ± 17.8
| |
12.7 ± 6.5
| |
- *According to 2010 American Joint Committee on Cancer (AJCC), Tis, T1, T2, or T3 colorectal cancer invades inside of colorectal serosa or non-peritonealized adjacent colorectal tissue; T4 gastric cancer invades outside of colorectal serosa or adjacent organs. U represents Mann–Whitney U-tests and T represents independent t-tests. Data were expressed as means ± standard deviations (Mean ± SD).